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Caspase inhibitors

Caspase inhibitors has been studied in 1 paper since 2025: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 4, 2025: “RNase L represses hair follicle regeneration through altered innate immune signaling”.

Intervention

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: AstraZeneca and others
  • Animals1

What did studies of Caspase inhibitors find?

1

Studies of Caspase inhibitors measured 1 outcome; the most studied are regeneration (1 study).

Regeneration

upin mice1

1 study

  1. Caspase inhibitors increase regeneration in mice.

    “pharmacologic inhibition of caspases promoted regeneration in an IL-36-dependent manner in multiple epithelial tissues”

    Animalsin multiple epithelial tissues

    RNase L represses hair follicle regeneration through altered innate immune signaling

    The Journal of clinical investigation

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