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Cartilage repair surgery

Cartilage repair surgery has been studied in 1 paper since 2025: 1 observational study in people. The newest paper, Mar 23, 2025: “Comparison of Three Different Techniques for the Treatment of Cartilage Lesions-Matrix-Induced Autologous Chondrocyte Implantation (MACI) Versus Autologous Matrix-Induced Chondrogenesis (AMIC) and Arthroscopic Minced Cartilage-A 2-Year Follow-Up on Patient-Reported Pain and Functional Outcomes”.

Exposure

1 paper studies it2 findingsUpdated

“Pain and function significantly improved from pre-surgery to two years after (VAS: p < 0.000; ES: η2 = 0.27; KOOS-Pain: p < 0.000; ES: η2 = 0.30”
Comparison of Three Different Techniques for the Treatment of Cartilage Lesions-Matrix-Induced Autologous Chondrocyte Implantation (MACI) Versus Autologous Matrix-Induced Chondrogenesis (AMIC) and Arthroscopic Minced Cartilage-A 2-Year Follow-Up on Patient-Reported Pain and Functional OutcomesJournal of clinical medicine2025doi:10.3390/jcm14072194

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • 2 of 2 findings with company ties
  • Humans1

What did studies of Cartilage repair surgery find?

2

Studies of Cartilage repair surgery measured 2 outcomes; the most studied are activity level (1 study) and pain (1).

Activity level

no changein humans1

1 study

  1. Cartilage repair surgery has no effect on activity level in humans.

    “There was no significant effect of time on the activity level.”

    Human trial2 yearsn = 48

    Comparison of Three Different Techniques for the Treatment of Cartilage Lesions-Matrix-Induced Autologous Chondrocyte Implantation (MACI) Versus Autologous Matrix-Induced Chondrogenesis (AMIC) and Arthroscopic Minced Cartilage-A 2-Year Follow-Up on Patient-Reported Pain and Functional Outcomes

    Journal of clinical medicine

Pain

downin humans1

1 study

  1. Cartilage repair surgery decreases pain in humans (p < 0.000, η2 = 0.27).

    “Pain and function significantly improved from pre-surgery to two years after (VAS: p < 0.000; ES: η2 = 0.27; KOOS-Pain: p < 0.000; ES: η2 = 0.30”

    Human trial2 yearsn = 48

    Comparison of Three Different Techniques for the Treatment of Cartilage Lesions-Matrix-Induced Autologous Chondrocyte Implantation (MACI) Versus Autologous Matrix-Induced Chondrogenesis (AMIC) and Arthroscopic Minced Cartilage-A 2-Year Follow-Up on Patient-Reported Pain and Functional Outcomes

    Journal of clinical medicine

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