Cardiovascular specialist referral
Intervention1 paper3 findings
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funders: Canadian Institutes of Health Research and 4 more3 of 3 findings with company ties
- Human trial1
Outcomes
3Cardiovascular events
no changein humans1
1 study
Cardiovascular events
no changein humans1
Cardiovascular specialist referral has no effect on cardiovascular events in humans (subdistribution hazard ratio, 1.08 (95% CI, 0.79-1.49)).
Human trialprostate cancermedian 5.8 yearsmalesn = 2,487
Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial · JAMA internal medicine · 30 Aug 2026
Cholesterol
downin humans1
1 study
Cholesterol
downin humans1
Cardiovascular specialist referral decreases cholesterol in humans (mean difference, 12 mg/dL (95% CI, 9-15 mg/dL)).
Human trialprostate cancermedian 5.8 yearsmalesn = 2,487
Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial · JAMA internal medicine · 30 Aug 2026
Hierarchical composite of cardiovascular outcomes and risk factors
upin humans1
1 study
Hierarchical composite of cardiovascular outcomes and risk factors
upin humans1
Cardiovascular specialist referral improves hierarchical composite of cardiovascular outcomes and risk factors in humans (win ratio 1.60 (95% CI, 1.42-1.81)).
Human trialprostate cancermedian 5.8 yearsmalesn = 2,487
Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial · JAMA internal medicine · 30 Aug 2026