Candida albicans

1. Candida albicans induce inflammation in mice.

   “often in close association with activated (Iba-1+) microglial cells.”

   Animalsin colonised germ-free micebrain

   Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

   Frontiers in aging neuroscience·Jul 18, 2022

More on Inflammation

1. Candida albicans induce fungal brain invasion in mice.

   “C. albicans was detected in different regions of the brain of colonised germ-free mice in both yeast and hyphal cell forms, often in close association with activated (Iba-1+) microglial cells.”

   Animalsin colonised germ-free micebrain

   Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

   Frontiers in aging neuroscience·Jul 18, 2022

1. Candida albicans increase lipofuscin in worms.

   “infection of C. albicans increases lipofuscin accumulation”

   Model organismsCandida albicans infection

   Regulation of DAF-16-mediated longevity and immune response to Candida albicans infection in Caenorhabditis elegans

   The new microbiologica·Dec 11, 2021

More on Lipofuscin

1. Candida albicans shorten lifespan in worms.

   “C. albicans is pathogenic to C. elegans and reduces the lifespan of C. elegans”

   Model organismsCandida albicans infection

   Regulation of DAF-16-mediated longevity and immune response to Candida albicans infection in Caenorhabditis elegans

   The new microbiologica·Dec 11, 2021