Calorie-carbohydrate restriction

Intervention

2 papers4 findings

  • 2 independent labs in 2 countries
  • Funders: Shahid Beheshti University of Medical Sciences and 1 more
  • Human trial2

Outcomes

4

Binge eating

no changein humans1

1 study
  1. Calorie-carbohydrate restriction has no effect on binge eating in humans.

    “In contrast, changes in BES and objective binge episodes were not significantly different between groups at any time point.”

    Human trialtype 2 diabetes

    Effects of intensive lifestyle interventions with calorie-carbohydrate-restricted diet versus time-restricted eating on appetite and binge eating in type 2 diabetes: A randomized controlled trial

    AppetiteJul 10, 2026

Satiety

upin humans1

1 study
  1. Calorie-carbohydrate restriction increases satiety in humans (21.7 mm (95% CI: 9.46, 33.9)).

    “Satiety also increased by 21.7 mm (95% CI: 9.46, 33.9) and 29.4 mm (95% CI: 17.4, 41.4), respectively.”

    Human trialtype 2 diabetes24 weeksn = 40

    Effects of intensive lifestyle interventions with calorie-carbohydrate-restricted diet versus time-restricted eating on appetite and binge eating in type 2 diabetes: A randomized controlled trial

    AppetiteJul 10, 2026

Hunger

downin humans1

1 study
  1. Calorie-carbohydrate restriction decreases hunger in humans (-24.1 mm (95% CI: -35.8, -12.5)).

    “At 24 weeks, hunger decreased by -24.1 mm (95% CI: -35.8, -12.5) in the CCR group”

    Human trialtype 2 diabetes24 weeksn = 40

    Effects of intensive lifestyle interventions with calorie-carbohydrate-restricted diet versus time-restricted eating on appetite and binge eating in type 2 diabetes: A randomized controlled trial

    AppetiteJul 10, 2026

Remission

upin humans1OR 11.7

1 study
  1. Calorie-carbohydrate restriction induces remission in humans (OR 11.7, 95% CI 1.4-98.3, p = 0.024).

    “Diabetes remission occurred in 9 (22.5%) of 40 participants in the CCR group (OR (CCR vs. Control) = 11.7, 95% CI: 1.4-98.3; p = 0.024)”

    Human trialtype 2 diabetes6 months

    The Effect of Integrated Lifestyle Intervention Incorporating Calorie-Carbohydrate Restriction With or Without Time-Restricted Feeding for Remission of Type 2 Diabetes (DIREM): A Single Blind Randomised Controlled Trial

    Endocrinology, diabetes & metabolismApr 12, 2026

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 02 in 12 months