CADD522

Intervention1 paper3 findingsPubChem 2834870

Animals1

Outcomes

3

Peripheral adiposity

downin mice1Very low certainty

1 study

CADD522 decreases peripheral adiposity in mice.
Animalsin an ovariectomy-induced mouse model25 mg/kgeight weeks
RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss · npj drug discovery · 7 Sep 2026

Marrow adiposity

downin mice1Very low certainty

1 study

CADD522 decreases marrow adiposity in mice.
Animalsin an ovariectomy-induced mouse model25 mg/kgeight weeks
RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss · npj drug discovery · 7 Sep 2026

Trabecular microarchitecture

upin mice1Very low certainty

1 study

CADD522 improves trabecular microarchitecture in mice.
Animalsin an ovariectomy-induced mouse modelbone25 mg/kgeight weeks
RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss · npj drug discovery · 7 Sep 2026

Latest

1

npj Drug DiscoveryAnimals8 Sep

RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss

Bones and joints