Brain health pro

Intervention

2 papers6 findings

  • 2 independent labs in 2 countries
  • Human trial2

Outcomes

6

Modifiable risk factors for alzheimer's disease

upin humans1

1 study
  1. Brain health pro improves modifiable risk factors for alzheimer's disease in humans.

    “BHPro, a relatively inexpensive web‐based multidomain intervention, improves key modifiable risk factors for Alzheimer's disease following a program duration of either 6 or 12 months.”

    Human trial12 monthsn = 353

    A web‐based multidomain intervention improves modifiable risk factors for Alzheimer's disease

    AAIC 2025 abstract23 Dec 2025

Physical activity

upin humans1

1 study
  1. Brain health pro improves physical activity in humans.

    “physical activity, nutrition, cognitive engagement, and sleep showed statistically significant improvements at both 6 and 12 months.”

    Human trial12 monthsn = 353

    A web‐based multidomain intervention improves modifiable risk factors for Alzheimer's disease

    AAIC 2025 abstract23 Dec 2025

Composite lifestyle risk score

upin humans1

1 study
  1. Brain health pro improves composite lifestyle risk score in humans (standardized change = 0.162, p < 0.001).

    “revealed a significant positive change in a composite lifestyle risk score at 6 months (standardized change = 0.162; p < 0.001)”

    Human trial6 monthsn = 353

    A web‐based multidomain intervention improves modifiable risk factors for Alzheimer's disease

    AAIC 2025 abstract23 Dec 2025

More on Composite lifestyle risk score

Diet and physical activity

upin humans1

1 study
  1. Brain health pro improves diet and physical activity in humans.

    “In the third profile, participants with lower baseline scores showed greater improvements in diet and physical activity, but no change was observed in vascular health.”

    Human triallower baseline scores in diet, physical activity and vascular health profile12 monthsn = 296

    Risk factor profiles and changes in risk factors and cognitive function over 12 months: The CAN‐THUMBS UP Brain Health Support Program Study

    AAIC 2025 abstract23 Dec 2025

Cognitive engagement

upin humans1

1 study
  1. Brain health pro improves cognitive engagement in humans.

    “Participants with lower baseline scores in the first two profiles showed greater improvements in associated risk factor domains compared to those with better baseline scores.”

    Human triallower baseline scores in cognitive engagement profile12 monthsn = 296

    Risk factor profiles and changes in risk factors and cognitive function over 12 months: The CAN‐THUMBS UP Brain Health Support Program Study

    AAIC 2025 abstract23 Dec 2025

Sleep, social and psychological health

upin humans1

1 study
  1. Brain health pro improves sleep, social and psychological health in humans.

    “Participants with lower baseline scores in the first two profiles showed greater improvements in associated risk factor domains compared to those with better baseline scores.”

    Human triallower baseline scores in sleep and social/psychological health profile12 monthsn = 296

    Risk factor profiles and changes in risk factors and cognitive function over 12 months: The CAN‐THUMBS UP Brain Health Support Program Study

    AAIC 2025 abstract23 Dec 2025

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