Bone marrow-derived c-kit+ cells

Intervention

1 paper studies it4 findings

Across all fields, 1 paper: none in people yet, 1 in animals

  • 1 lab in 1 country
  • Funders: Tabriz University of Medical Sciences and 1 more
  • Animals1

Outcomes

4

FSH

no changein rats1

1 study
  1. Bone marrow-derived c-kit+ cells have no effect on FSH in rats.

    “Systemic levels of FSH did not significantly change in pre- or post-transplantation time points for any group (P > 0.05).”

    Animalsin a rat model of premature ovarian failureovaryfemales

    Intra-ovarian injection of bone marrow-derived c-Kit⁺ cells for ovarian rejuvenation in menopausal rats

    BioImpacts : BI

More on FSH

Fertility rate

upin rats1

1 study
  1. Bone marrow-derived c-kit+ cells improve fertility rate in rats.

    “Transplantation of c-Kit+ cells also restored the reduced fertility rate (P < 0.05).”

    Animalsin a rat model of premature ovarian failureovaryfemales

    Intra-ovarian injection of bone marrow-derived c-Kit⁺ cells for ovarian rejuvenation in menopausal rats

    BioImpacts : BI

Collagen deposition

downin rats1

1 study
  1. Bone marrow-derived c-kit+ cells decrease collagen deposition in rats.

    “Notable reduction of collagen deposition was found in c-Kit-treated rats.”

    Animalsin a rat model of premature ovarian failureovaryfemales

    Intra-ovarian injection of bone marrow-derived c-Kit⁺ cells for ovarian rejuvenation in menopausal rats

    BioImpacts : BI

Atretic follicles

downin rats1

1 study
  1. Bone marrow-derived c-kit+ cells decrease atretic follicles in rats.

    “Histological examination revealed a substantial reduction of atretic follicles in POF rats receiving c-Kit+ cells in comparison with POF rats that did not receive these cells (P < 0.05).”

    Animalsin a rat model of premature ovarian failureovaryfemales

    Intra-ovarian injection of bone marrow-derived c-Kit⁺ cells for ovarian rejuvenation in menopausal rats

    BioImpacts : BI

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