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Bone cement

Bone cement has been studied in 5 papers since 2021: 4 observational studies in people, 1 review. The newest paper, Oct 1, 2025: “Risk Factors for Perioperative Myocardial Infarction/Injury and Mortality Following Surgical Treatment of Proximal Femur Fractures: A Cohort Study”.

Intervention

5 papers study it3 findingsUpdated

See all 5

“The use of cement was correlated with higher mortality rate: HR = 1.107 (1.067-1.149) p < 0.0001.”
Reduced mortality associated to cementless total hip arthroplasty in femoral neck fractureScientific reports2023doi:10.1038/s41598-023-43790-8

1 of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

  • 3 independent labs in 2 countries
  • 1 finding against
  • Humans4

What did studies of Bone cement find?

1

Studies of Bone cement measured 1 outcome; the most studied are mortality (2 studies).

Mortality

no changein humans2

2 studies

  1. Bone cement has no effect on mortality in humans.

    “No significant effects were seen for gender or cement use on functional outcomes and mortality.”

    Humansin patients with metastatic humeral fractures treated with nails

    Which Factors Affect Functional Outcomes and Survival in Metastatic Humeral Fractures Treated With Nails?

    Orthopaedic surgery

  2. Bone cement has no effect on mortality in humans.

    “No significant difference was observed between the two groups in mortality at any follow-up period.”

    Reviewn = 1,599

    Mortality associated with cemented and uncemented fixation of hemiarthroplasty and total hip replacement in the surgical management of intracapsular hip fractures: A systematic review and meta-analysis

    Injury

What is Bone cement linked with?

1

Studies link Bone cement with 1 measure, most often mortality (1 study).

Mortality

upin humans1HR 1.107

1 study

  1. Bone cement raises the risk of mortality in humans (HR = 1.107 (1.067-1.149)).

    “The use of cement was correlated with higher mortality rate: HR = 1.107 (1.067-1.149) p < 0.0001.”

    Humansmultivariate analysis including age, gender, comorbidities/autonomy scores, social category, and obesity2 yearsn = 96,184

    Reduced mortality associated to cementless total hip arthroplasty in femoral neck fracture

    Scientific reports

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