BMP-2-IMMOBILIZED nanofibers

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Ministry of Health and Welfare and 2 more
4 of 4 findings with company ties

Animals1

Outcomes

Bone regeneration

upin humans1

1 study

BMP-2-IMMOBILIZED nanofibers increase bone regeneration in humans (73.5 ± 5.9% HNA+OPN+ cells).
Animalscalvarial defect model at 8 weeks8 weeks
Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs
Biomaterials13 Aug 2026

Microvascular density

upin humans1

1 study

BMP-2-IMMOBILIZED nanofibers increase microvascular density in humans.
Animalssubcutaneous implantation of hydrogels
Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs
Biomaterials13 Aug 2026

Osteogenic differentiation

upin human cells1

1 study

BMP-2-IMMOBILIZED nanofibers increase osteogenic differentiation in human cells.
Cellsin co-culture spheroids compared with conventional BMP-2 delivery
Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs
Biomaterials13 Aug 2026

Angiogenic sprouting

upin human cells1

1 study

BMP-2-IMMOBILIZED nanofibers increase angiogenic sprouting in human cells.
Cellsin co-culture spheroids compared with conventional BMP-2 delivery
Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs
Biomaterials13 Aug 2026

Latest

1 in 12 months

Biomaterials18 Aug

Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs

Experiments in animalsBones and joints

Paper

BMP-2-IMMOBILIZED nanofibers

Outcomes

Latest

Intra-spheroidal BMP-2 delivery in co-cultured spheroids enables concurrent vasculogenesis and osteogenesis in 3D engineered bone constructs

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