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Beta-amyrin

Intervention

1 paper2 findings

PubChem 73145ChEBI 10352MeSH C036380

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Center for Geriatrics and Gerontology and 1 more
  • 2 of 2 findings with company ties
  • Cells1

Outcomes

1

Senescent-cell death

upin human cells1upin mouse cells1

1 study

  1. Beta-amyrin induces senescent-cell death in human cells.

    “β-amyrin selectively induced cell death in senescent cells.”

    Cellsin senescent fibroblasts

    Senolytic potential of shea-derived amyrins in senescent fibroblasts

    Bioscience, biotechnology, and biochemistry24 Oct 2025

  2. Beta-amyrin induces senescent-cell death in mouse cells.

    “β-amyrin selectively induced cell death in senescent cells.”

    Cellsin senescent fibroblasts

    Senolytic potential of shea-derived amyrins in senescent fibroblasts

    Bioscience, biotechnology, and biochemistry24 Oct 2025

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