AgingResearch.NewsJoin free

Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1

Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 has been studied in 1 paper since 2009: 1 trial in people. The newest paper, Dec 19, 2009: “Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial”.

Intervention

1 paper studies it3 findingsUpdated

“At 14 weeks, the treatment arm exhibited an estimated 31% mean reduction (P = 0.02) in serum osteocalcin”
Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trialJournal of bone and mineral metabolism2009doi:10.1007/s00774-009-0141-z

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Human trial1

What did studies of Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 find?

3

Studies of Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 measured 3 outcomes; the most studied are IGF-1 (1 study), 25-hydroxyvitamin D (1) and osteocalcin (1).

IGF-1

upin humans1

1 study

  1. Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 increases IGF-1 in humans (P < 0.01).

    “Serum IGF-I was increased in both arms, but the increase was more significant in the treatment arm at 14 weeks (P < 0.01).”

    Human trialserum200 mg hop rho iso-alpha acids, 100 mg berberine sulfate trihydrate, 500 IU vitamin D(3) and 500 microg vitamin K(1), twice daily14 weeksfemales

    Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial

    Journal of bone and mineral metabolism

More on IGF-1

25-hydroxyvitamin D

upin humans1

1 study

  1. Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 increases 25-hydroxyvitamin D in humans (+13% (P = 0.24) vs -25% (P < 0.01) in placebo).

    “Serum 25-hydroxyvitamin D (25(OH)D) increased by 13% (P = 0.24) in the treatment arm and decreased by 25% (P < 0.01) in the placebo arm.”

    Human trialserum200 mg hop rho iso-alpha acids, 100 mg berberine sulfate trihydrate, 500 IU vitamin D(3) and 500 microg vitamin K(1), twice daily14 weeksfemales

    Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial

    Journal of bone and mineral metabolism

More on 25-hydroxyvitamin D

Osteocalcin

downin humans1

1 study

  1. Hop rho iso-alpha acids + berberine + vitamin D3 + vitamin K1 decreases osteocalcin in humans (-31% mean reduction (P = 0.02)).

    “At 14 weeks, the treatment arm exhibited an estimated 31% mean reduction (P = 0.02) in serum osteocalcin”

    Human trialserum200 mg hop rho iso-alpha acids, 100 mg berberine sulfate trihydrate, 500 IU vitamin D(3) and 500 microg vitamin K(1), twice daily14 weeksfemales

    Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial

    Journal of bone and mineral metabolism

More on Osteocalcin

Latest

Related