Anti-i-j monoclonal antibody

Anti-i-j monoclonal antibody has been studied in 1 paper since 1984: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 31, 1984: “Effects of long-term treatment of mice with anti-I-J monoclonal antibody and dialyzable leukocyte extract on immune function and lifespan”.

Intervention

1 paper studies it3 findingsUpdated

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Medical University of South Carolina and 2 more
  • Animals1

What did studies of Anti-i-j monoclonal antibody find?

3

Studies of Anti-i-j monoclonal antibody measured 3 outcomes; the most studied are lifespan (1 study), secondary antibody response (1) and T-helper cells (1).

Lifespan

upin mice1

1 study
  1. Anti-i-j monoclonal antibody extends lifespan in mice.

    “Mice treated with anti-I-J antibody survived longer than did mice of the other two groups.”

    Animalsweekly treatment compared to saline and dialyzable leukocyte extract

    Effects of long-term treatment of mice with anti-I-J monoclonal antibody and dialyzable leukocyte extract on immune function and lifespan

    Mechanisms of ageing and development

Secondary antibody response

upin mice1

1 study
  1. Anti-i-j monoclonal antibody increases secondary antibody response in mice.

    “Both types of immunologic intervention resulted in a greater secondary antibody response than that of the saline-treated control mice.”

    Animalsimmunized with avian gammaglobulin at 27 and 29 months of age

    Effects of long-term treatment of mice with anti-I-J monoclonal antibody and dialyzable leukocyte extract on immune function and lifespan

    Mechanisms of ageing and development

More on Secondary antibody response

T-helper cells

upin mice1

1 study
  1. Anti-i-j monoclonal antibody increases T-helper cells in mice.

    “Mice treated with anti-I-J antibody had elevated T-helper cell activity.”

    Animalstreated once a week for one yearspleen1 year

    Effects of long-term treatment of mice with anti-I-J monoclonal antibody and dialyzable leukocyte extract on immune function and lifespan

    Mechanisms of ageing and development

More on T-helper cells

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