Anesthesia/surgery

1. Anesthesia/surgery increases inflammation in mice.

   “enhanced the activation of microglia and astrocytes in the hippocampus of aged mice”

   Animalsafter anesthesia/surgeryhippocampusmales

   Pericyte loss impairs the blood-brain barrier and cognitive function in aged mice after anesthesia/surgery

   Brain research bulletin·Oct 29, 2023

More on Inflammation

1. Anesthesia/surgery impairs blood-brain barrier integrity in mice.

   “reduced pericyte coverage, decreased the length of capillaries and levels of occludin and claudin-5, destroyed the structure of the BBB”

   Animalsafter anesthesia/surgeryhippocampusmales

   Pericyte loss impairs the blood-brain barrier and cognitive function in aged mice after anesthesia/surgery

   Brain research bulletin·Oct 29, 2023

1. Anesthesia/surgery impairs cognitive function in mice.

   “Anesthesia/Surgery damaged cognitive function”

   Animalsafter anesthesia/surgerybrainmales

   Pericyte loss impairs the blood-brain barrier and cognitive function in aged mice after anesthesia/surgery

   Brain research bulletin·Oct 29, 2023