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Anabolic-androgenic steroids

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • Animals1

Outcomes

2

Mortality

upin mice1

1 study

  1. Anabolic-androgenic steroids increase mortality in mice (52% vs 12% (P < 0.001)).

    “52% of the mice given the high dose of steroids had died compared with 35% of the mice given the low dose and only 12% of the control mice given no exogenous hormones (P < 0.001)”

    Animals6 monthsmales

    Exposure to anabolic-androgenic steroids shortens life span of male mice

    Medicine and science in sports and exercise1 May 1997

Lifespan

downin mice1

1 study

  1. Anabolic-androgenic steroids shorten lifespan in mice (52% vs 35% vs 12% mortality (P < 0.001)).

    “the life span of male mice is decreased dramatically by exposing them for 6 months to the kinds and relative levels of anabolic steroids”

    Animals6 monthsmales

    Exposure to anabolic-androgenic steroids shortens life span of male mice

    Medicine and science in sports and exercise1 May 1997

Associations

1

Tumor

upin mice1

1 study

  1. Anabolic-androgenic steroids raise the risk of tumor in mice.

    “Autopsy of the steroid-treated mice typically revealed tumors in the liver or kidney, other kinds of damage to these two organs, broadly invase lymphosarcomas, or heart damage”

    Animals6 monthsmales

    Exposure to anabolic-androgenic steroids shortens life span of male mice

    Medicine and science in sports and exercise1 May 1997

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