Ammonium nitrate
Ammonium nitrate has been studied in 1 paper since 2016: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 16, 2016: “Partial Reversal of Tissue Calcification and Extension of Life Span following Ammonium Nitrate Treatment of Klotho-Deficient Mice”.
1 new paper in 30 daysSee all 5 papers on ammonium nitrate
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funder: Deutsche Forschungsgemeinschaft
- Animals1
What did studies of ammonium nitrate find?
4Studies of ammonium nitrate measured 4 outcomes; the most studied are plasma 1,25(OH)2D3 (1 study), blood pCO2 (1) and tissue calcification (1).
Plasma 1,25(OH)2D3
no changein mice1
1 study
Plasma 1,25(OH)2D3
no changein mice1
Ammonium nitrate showed no clear effect on plasma 1,25(OH)2D3 in mice.
“without significantly affecting extracellular pH or plasma concentrations of 1,25(OH)2D3, Ca2+, phosphate, Na+, and K+”
Animals0.28 M in drinking water
Kidney & blood pressure research
Blood pCO2
downin mice1
1 study
Blood pCO2
downin mice1
Ammonium nitrate decreases blood pCO2 in mice.
“NH4NO3-treatment decreased both, blood pCO2 and HCO3-”
Animals0.28 M in drinking water
Kidney & blood pressure research
Tissue calcification
downin mice1
1 study
Tissue calcification
downin mice1
Ammonium nitrate decreases tissue calcification in klotho-hypomorphic (kl/kl) mice.
“decreased calcification of trachea, lung, kidney, stomach, heart and vessels”
Animalsin klotho-hypomorphic (kl/kl) micetrachea, lung, kidney, stomach, heart, vessels0.28 M in drinking water
Kidney & blood pressure research
Lifespan
upin mice1
1 study
Lifespan
upin mice1
Ammonium nitrate extends lifespan in klotho-hypomorphic (kl/kl) mice (more than 1.7-fold (male), 1.6-fold (female)).
“increased the life span of kl/kl mice more than 1.7-fold (♂) or 1.6-fold (♀)”
Animalsin klotho-hypomorphic (kl/kl) mice0.28 M in drinking water
Kidney & blood pressure research