Alpha-glycerophosphocholine

Intervention

1 paper studies it3 findings

Across all fields, 1 paper: none in people yet, 1 in animals

  • 1 lab in 1 country
  • Funders: Council for Science, Technology and Innovation and 3 more
  • Animals1

Outcomes

3

Doublecortin-positive cells

upin mice1

1 study
  1. Alpha-glycerophosphocholine increases doublecortin-positive cells in mice.

    “The GPC intake suppressed microglial activation and BBB disruption and sustained doublecortin-positive cells in the hippocampus.”

    Animalsin SAMP8 micehippocampus

    Long-term intake of α-glycerophosphocholine (GPC) suppresses microglial inflammation and blood-brain barrier (BBB) disruption and promotes neurogenesis in senescence-accelerated mice prone 8 (SAMP8)

    Bioscience, biotechnology, and biochemistry

More on Doublecortin-positive cells

Blood-brain barrier disruption

downin mice1

1 study
  1. Alpha-glycerophosphocholine decreases blood-brain barrier disruption in mice.

    “The GPC intake suppressed microglial activation and BBB disruption and sustained doublecortin-positive cells in the hippocampus.”

    Animalsin SAMP8 micebrain

    Long-term intake of α-glycerophosphocholine (GPC) suppresses microglial inflammation and blood-brain barrier (BBB) disruption and promotes neurogenesis in senescence-accelerated mice prone 8 (SAMP8)

    Bioscience, biotechnology, and biochemistry

Microglial activation

downin mice1

1 study
  1. Alpha-glycerophosphocholine decreases microglial activation in mice.

    “The GPC intake suppressed microglial activation and BBB disruption and sustained doublecortin-positive cells in the hippocampus.”

    Animalsin SAMP8 micebrain

    Long-term intake of α-glycerophosphocholine (GPC) suppresses microglial inflammation and blood-brain barrier (BBB) disruption and promotes neurogenesis in senescence-accelerated mice prone 8 (SAMP8)

    Bioscience, biotechnology, and biochemistry

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