Aged regulatory t-cell therapy
Aged regulatory t-cell therapy has been studied in 1 paper since 2025: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Mar 7, 2025: “Aged regulatory T cells fail to control autoimmune lacrimal gland pathogenic CD4⁺ T cells”.
1 paper studies it1 findingUpdated
- 1 lab in 1 country
- Funders: Agencia Nacional de Promoción Científica y Tecnológica and 6 more
- Animals1
What did studies of Aged regulatory t-cell therapy find?
1Studies of Aged regulatory t-cell therapy measured 1 outcome; the most studied are inflammation (1 study).
Inflammation
upin mice1
1 study
Inflammation
upin mice1
Aged regulatory t-cell therapy increases inflammation in mice (co-adoptive transfer with CD25KO CD4+ T cells in RAG1KO mice compared to young Tregs).
“Recipients of CD25KO CD4+ T cells with aged B6 Tregs had more inflamed LGs than young Tregs”
Animalsco-adoptive transfer with CD25KO CD4+ T cells in RAG1KO mice compared to young Tregslacrimal gland
Aged regulatory T cells fail to control autoimmune lacrimal gland pathogenic CD4⁺ T cells
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