Adjuvanted component varicella zoster virus vaccine
1 paper3 findings
- 1 lab
- Humans1
Outcomes
3CD8+ T cell defects
no changein humans1
1 study
CD8+ T cell defects
no changein humans1
Adjuvanted component varicella zoster virus vaccine has no effect on CD8+ T cell defects in humans.
“Vaccination of older adults with the adjuvanted vaccine did not restore CD8+ defects”
Human trial
Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity
Science advances6 Feb 2026
Conversion of TH17 cells into regulatory T cells
downin humans1
1 study
Conversion of TH17 cells into regulatory T cells
downin humans1
Adjuvanted component varicella zoster virus vaccine prevents conversion of TH17 cells into regulatory T cells in humans.
“selectively enhanced T helper 17 (TH17) CD4+ T cells and prevented their conversion into regulatory T cells”
Human trial
Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity
Science advances6 Feb 2026
TH17 CD4+ T cells
upin humans1
1 study
TH17 CD4+ T cells
upin humans1
Adjuvanted component varicella zoster virus vaccine increases TH17 CD4+ T cells in humans.
“Vaccination of older adults with the adjuvanted vaccine did not restore CD8+ defects but selectively enhanced T helper 17 (TH17) CD4+ T cells”
Human trial
Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity
Science advances6 Feb 2026