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Betaine + acetylcysteine + levocarnitine + nicotinamide riboside

Intervention

1 paper studies it4 findings

PubChemPubChemPubChemPubChemChEBIChEBIChEBIChEBI

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Centre Tecnològic de Catalunya and 3 more
  • 4 of 4 findings with company ties
  • Animals1

Outcomes

4

Thermogenesis

upin mice1

1 study

  1. Betaine + acetylcysteine + levocarnitine + nicotinamide riboside increases thermogenesis in mice.

    “decreased fat accumulation in BAT, raising non-shivering thermogenesis”

    Animalsin high-fat diet-induced obese micecombinationbrown adipose tissue4 weeks

    Reduction of Obesity and Insulin Resistance through Dual Targeting of VAT and BAT by a Novel Combination of Metabolic Cofactors

    International journal of molecular sciences

Fatty acid β-oxidation

upin mice1

1 study

  1. Betaine + acetylcysteine + levocarnitine + nicotinamide riboside increases fatty acid β-oxidation in mice.

    “an important improvement in lipid oxidation”

    Animalsin high-fat diet-induced obese micecombinationepididymal white adipose tissue4 weeks

    Reduction of Obesity and Insulin Resistance through Dual Targeting of VAT and BAT by a Novel Combination of Metabolic Cofactors

    International journal of molecular sciences

More on Fatty acid β-oxidation

Insulin resistance

downin mice1

1 study

  1. Betaine + acetylcysteine + levocarnitine + nicotinamide riboside decreases insulin resistance in mice.

    “MC supplementation reduced glucose intolerance and insulin resistance”

    Animalsin high-fat diet-induced obese micecombination4 weeks

    Reduction of Obesity and Insulin Resistance through Dual Targeting of VAT and BAT by a Novel Combination of Metabolic Cofactors

    International journal of molecular sciences

More on Insulin resistance

Obesity

downin mice1

1 study

  1. Betaine + acetylcysteine + levocarnitine + nicotinamide riboside decreases obesity in mice.

    “MC supplementation conferred a moderate reduction of obesity and adiposity”

    Animalsin high-fat diet-induced obese micecombination4 weeks

    Reduction of Obesity and Insulin Resistance through Dual Targeting of VAT and BAT by a Novel Combination of Metabolic Cofactors

    International journal of molecular sciences

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