Aav-themis

1 paper2 findings

1 lab in 1 country

Funder: University of Michigan

Animals1

Outcomes

2

Cellular senescence

downin mice1

1 study

Aav-themis inhibits cellular senescence in mice.
“adeno-associated virus-mediated overexpression of THEMIS suppressed hepatocyte senescence”
Animalsdiet-induced MASHliver
THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice
The Journal of clinical investigation1 May 2026

More on Cellular senescence

Metabolic dysfunction-associated steatohepatitis

downin mice1

1 study

Aav-themis protects against metabolic dysfunction-associated steatohepatitis in mice.
“overexpression of THEMIS suppressed hepatocyte senescence and attenuated diet-induced MASH”
Animalsdiet-induced MASHliver
THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice
The Journal of clinical investigation1 May 2026

More on Metabolic dysfunction-associated steatohepatitis

Latest

1 in 12 months

The Journal of Clinical Investigation1 May

THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice

Experiments in miceCellular senescence