Aav-bdnf

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 1 more
  • Animals1

Outcomes

3

Anxiety-like and depression-like behaviors

downin mice1

1 study
  1. Aav-bdnf decreases anxiety-like and depression-like behaviors in mice.

    “BDNF treatment reduced anxiety-like and depression-like behaviors”

    Animalshypothalamus28 weeks

    Hypothalamic gene transfer of BDNF promotes healthy aging in mice

    Aging cell26 Dec 2018

Inflammation

downin mice1

1 study
  1. Aav-bdnf decreases inflammation in mice.

    “suppressing inflammatory genes in the hypothalamus and adipose tissues”

    Animalshypothalamus28 weeks

    Hypothalamic gene transfer of BDNF promotes healthy aging in mice

    Aging cell26 Dec 2018

More on Inflammation

Weight gain

downin mice1

1 study
  1. Aav-bdnf prevents weight gain in mice.

    “preventing aging-associated weight gain, reducing adiposity, reversing the decline of brown fat activity”

    Animalshypothalamus28 weeks

    Hypothalamic gene transfer of BDNF promotes healthy aging in mice

    Aging cell26 Dec 2018

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