3d-bioprinted dual-factor nerve conduit

3d-bioprinted dual-factor nerve conduit increases gastrocnemius muscle preservation in rats.

“greater gastrocnemius muscle preservation than the untreated control.”

Animals10-mm sciatic nerve defect; compared with untreated controlNGF + VEGF + SC-SHED conduitgastrocnemius muscle1 and 3 months

3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways

Biomaterials·Oct 15, 2026

3d-bioprinted dual-factor nerve conduit improves sensorimotor function in rats.

“better electrophysiological and sensorimotor outcomes, and greater gastrocnemius muscle preservation than the untreated control.”

Animals10-mm sciatic nerve defect; compared with untreated controlNGF + VEGF + SC-SHED conduit1 and 3 months

3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways

Biomaterials·Oct 15, 2026

3d-bioprinted dual-factor nerve conduit improves myelin morphometry in rats.

“the NGF + VEGF + SC-SHED group showed increased microvessel density, stronger S100β- and NF200-associated signals, improved myelin morphometry”

Animals10-mm sciatic nerve defect; compared with untreated controlNGF + VEGF + SC-SHED conduitsciatic nerve1 and 3 months

3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways

Biomaterials·Oct 15, 2026

3d-bioprinted dual-factor nerve conduit increases microvessel density in rats.

“the NGF + VEGF + SC-SHED group showed increased microvessel density”

Animals10-mm sciatic nerve defect; compared with untreated controlNGF + VEGF + SC-SHED conduitsciatic nerve1 and 3 months

3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways

Biomaterials·Oct 15, 2026