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wts-1

Gene

2 papers3 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Research Foundation and 4 more
  • Model organisms2

Effects

2

Touch neuron deformation

downin worms2

2 studies

  1. wts-1 protects against touch neuron deformation in worms.

    “Loss of wts-1/LATS, the core kinase of the Hpo pathway, resulted in premature deformation of touch neurons”

    Model organismsin wts-1 mutants

    Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

    eLife14 Mar 2025Preprint

  2. wts-1 decreases touch neuron deformation in worms.

    “Loss of wts-1/LATS resulted in premature deformation of touch neurons and impaired touch responses in a yap-1/YAP-dependent manner.”

    Model organismsShown by loss of wts-1; yap-1-dependenttouch neuron

    Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

    eLife20 Dec 2024Preprint

Touch responses

upin worms1

1 study

  1. wts-1 improves touch responses in worms.

    “Loss of wts-1/LATS resulted in premature deformation of touch neurons and impaired touch responses in a yap-1/YAP-dependent manner.”

    Model organismsShown by loss of wts-1; yap-1-dependenttouch neuron

    Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

    eLife20 Dec 2024Preprint

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