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Ubc-E2M

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Canadian Institutes of Health Research and others
  • 1 of 1 finding with company ties
  • Cells1

Effects

1

Muscle defects

downin flies1

1 study

  1. Ubc-E2M decreases muscle defects in flies.

    “overexpression of UbcE2M, one of the proteins targeted for NatC KO-mediated degradation, suppresses defects of NatC deletion”

    Model organismsmuscle-specific overexpression in NatC deletion fliesmuscle

    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

    Nature communications

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