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TOMM40/APOELOCUS

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 2 countries
  • Funders: Diabetes Research and Wellness Foundation and 8 more
  • Humans1

Associations

1

Longevity

mixedin humans1

1 study

  1. TOMM40/APOELOCUS is associated with longevity in humans.

    “In candidate analyses, variants in the TOMM40/APOE locus were associated with longevity, but FOXO variants were not.”

    HumansCandidate variant analyses

    Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

    Aging

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