Free Radical Biology & Medicine
Sorcin protein helped scar-forming liver cells keep dividing
Experiments in liver stellate cells traced the effect to RNA-containing clusters that reduced production of p53, a protein that helps regulate cell division.Experiments in liver stellate cells traced the effect to RNA-containing clusters that reduced production of p53, a protein that helps regulate cell division.
Cell studyMechanisms
Who was studiedHepatic stellate cells
What changedSorcin increased liver stellate cells' capacity to multiply and reduced signs of senescence
The catchThe continued-division claim rests on senescence markers and proliferative capacity