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smg-2

Gene

1 paper1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Department of Biotechnology, Ministry of Science and Technology, India and 3 more
  • Model organisms1

Effects

1

Lifespan

is required forin worms1

1 study

  1. smg-2 is required for lifespan in worms.

    “knocking down UPF1 homologue smg-2 suppresses DR lifespan”

    Model organismsduring dietary restriction

    Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity

    Nature communications21 Aug 2017

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