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RS7220676

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Alzheimer's Disease Neuroimaging Initiative and others
  • Humans1

Associations

2

Cognitive function

mixedin humans1

1 study

  1. RS7220676 is associated with cognitive function in humans.

    “rs7220676 was correlated with rates of cognitive decline assessed by Mini-mental State Examination and memory scores.”

    Humansn = 350

    Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia

    NeuroImage. Clinical6 Feb 2020

White matter hyperintensity volume

downin humans1

1 study

  1. RS7220676 is associated with white matter hyperintensity volume in humans (P = 2.96 × 10−8).

    “The minor allele of rs7220676 (C) showed association with lower log (WMHV) in a dose-dependent manner.”

    Humansadditive genetic modelbrainn = 350

    Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia

    NeuroImage. Clinical6 Feb 2020

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