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Age-linked RNA splicing changes are widespread in human tissues
An analysis of 17,382 human tissue samples linked age to splicing changes in 10,786 genes, or 70% of those tested.An analysis of 17,382 human tissue samples linked age to splicing changes in 10,786 genes, or 70% of those tested.
Preprint: cross-sectional studyRNA splicing
Who was studiedHuman tissue donors
What changedRNA splicing varied with age in 10,786 genes (70%) across human tissues
The catchAge-linked death circumstances account for much of the tissue-to-tissue variation in splicing associations