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RFA2

Gene

1 paper1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Directorate for Biological Sciences and 5 more
  • Cells1

Effects

1

Telomere length

downin yeast cells1

1 study

  1. RFA2 decreases telomere length in yeast cells.

    “mutations in RPA2 that confer an Est (Ever shorter telomeres) phenotype, characteristic of a defect in the telomerase pathway”

    CellsRPA2 mutations

    The canonical RPA complex interacts with Est3 to regulate yeast telomerase activity

    Proceedings of the National Academy of Sciences of the United States of AmericaFeb 6, 2025

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