RBPMS

4 papers study it2 findings

HGNC NCBI Gene Taxon

None of its findings points the other way.

1 lab in 1 country

Funders: National Cancer Institute and 3 more

Humans1
Animals3

Effects

2

Cell cycle regulation

downin human cells1

1 study

RBPMS inhibits cell cycle regulation in human cells.
“RBPMS knockout clones grew faster and had increased invasiveness than the control CRISPR clones”
Cellsshown by knockout in OVCAR3 cells
Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells
International journal of molecular sciencesJan 4, 2022

More on Cell cycle regulation

Lifespan

upin humans1

1 study

RBPMS extends lifespan in humans.
“ovarian cancer patients with high RBPMS levels live longer compared to patients with low RBPMS levels”
Humansin ovarian cancer patients
Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells
International journal of molecular sciencesJan 4, 2022

Latest

2 papers in 12 months

Investigative Ophthalmology & Visual ScienceMar 27

AAV2-Retro-Mediated Gene Transfer Selectively Targets Outer Retinal Cells Following Intravitreal Injection

Experiments in miceEye

bioRxivMar 12

AAV2-Retro-Mediated Gene Transfer Selectively Targets Outer Retinal Cells Following Intravitreal Injection

Preprint: experiments in miceEye

Investigative Ophthalmology & Visual ScienceApr 8

Comparison of Brn3a and RBPMS Labeling to Assess Retinal Ganglion Cell Loss During Aging and in a Model of Optic Neuropathy

Experiments in miceBiomarkers

International Journal of Molecular SciencesJan 12

Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

Study in peopleReproductive system