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poe

Gene

1 paper1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: American Federation for Aging Research and others
  • Animals1

Effects

1

Lifespan

downin flies1

1 study

  1. poe shortens lifespan in flies.

    “shortens lifespan in Drosophila by reducing protein quality control.”

    Model organismsmuscle-specific loss

    Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging

    Nature communications3 Mar 2021

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