AgingResearch.NewsJoin free

PIP5K1C

Gene

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 4 more
  • Animals1

Effects

3

Apoptosis

downin mice1

1 study

  1. PIP5K1C prevents apoptosis in mice.

    “promoted apoptosis”

    Animalsosteocyte-specific deletion

    Pip5k1c expression in osteocytes regulates bone remodeling in mice

    Journal of orthopaedic translation8 Mar 2024

More on Apoptosis

Biomechanical properties

downin mice1

1 study

  1. PIP5K1C impairs biomechanical properties in mice.

    “impaired biomechanical properties in femur”

    Animalsosteocyte-specific deletionfemur

    Pip5k1c expression in osteocytes regulates bone remodeling in mice

    Journal of orthopaedic translation8 Mar 2024

Bone mass

downin mice1

1 study

  1. PIP5K1C decreases bone mass in mice.

    “Loss of Pip5k1c in osteocytes led to a low bone mass in long bones and spines and impaired biomechanical properties in femur”

    Animalsosteocyte-specific deletion

    Pip5k1c expression in osteocytes regulates bone remodeling in mice

    Journal of orthopaedic translation8 Mar 2024

Latest

Related