pdfr-1

Gene1 paper1 findingTaxon 6239

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.

1 lab in 1 country
  • Model organisms1

Effects

1

Lifespan

mediatesin worms1

1 study
  1. pdfr-1 mediates lifespan in worms.

    Model organismsenterobactin-driven changes under redox modulationneuron

    Bacterial molecule shapes behaviour and lifespan in worms · bioRxiv · 8 Oct 2026 · Preprint

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bioRxivModel organismsPreprint

Bacterial molecule shapes behaviour and lifespan in worms

A screen of 3,985 bacterial strains identified an iron-gathering molecule whose effects in worms depended on a stress response in cells’…A screen of 3,985 bacterial strains identified an iron-gathering molecule whose effects in worms depended on a stress response in cells’ energy-producing structures.