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PDE7A

There are 3 papers on PDE7A in aging research: 1 observational study in people, 1 in animals, 1 review.

Gene

3 papers study it1 finding

HGNCNCBI GeneTaxon

See all 3 papers on PDE7A

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country; 6 trials, 3 with no results posted.

“glaucoma with rs10808746 with immediate story recall (P < 0.05).”
Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on AgingInvestigative ophthalmology & visual science2025doi:10.1167/iovs.66.6.71
Humans: a single group. Cells, worms or flies and mice: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

No results posted: trials that ended over a year ago with no results on ClinicalTrials.gov and no paper reporting them.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 6 trials, 3 with no results posted
  • Funders: Gouvernement du Canada | Canadian Institutes of Health Research and 1 more
  • 5 of 6 trials sponsored by developers of drugs aimed at it
  • Humans1
  • Animals1

Associations

1

Cognitive function

mixedin humans1

1 study

  1. PDE7A is associated with cognitive function in linear regression models for interaction (P < 0.05).

    “glaucoma with rs10808746 with immediate story recall (P < 0.05).”

    Humansin linear regression models for interaction

    Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on Aging

    Investigative ophthalmology & visual science

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