PCAT14
1 paper2 findings
- 1 lab in 1 country
- Funders: Alexander S. Onassis Public Benefit Foundation and 3 more
- Cells1
Upstream
1Advanced age
downin human cells1
1 study
Advanced age
downin human cells1
Advanced age decreases PCAT14 in human cells.
“PCAT14 is relatively abundant, localized almost exclusively in the nucleus of young endothelial cells, and silenced in the aged endothelium.”
Cellsin advanced ageartery
Unravelling the impact of aging on the human endothelial lncRNA transcriptome
Frontiers in geneticsOct 21, 2022
Associations
1Inflammation
mixedin human cells1
1 study
Inflammation
mixedin human cells1
PCAT14 is associated with inflammation in human cells.
“downregulation of PCAT14 alters endothelial cell transcription profile and cell functions including endothelial cell migration, sprouting and inflammatory responses in vitro.”
Cellsin vitro
Unravelling the impact of aging on the human endothelial lncRNA transcriptome
Frontiers in geneticsOct 21, 2022
Latest
Frontiers in Genetics
Unravelling the impact of aging on the human endothelial lncRNA transcriptome
Experiments in human cellsMechanisms