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PaMth1

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Deutsche Forschungsgemeinschaft and 1 more
  • Cells1

Effects

2

Protein carbonylation

downin P. anserina cells1

1 study

  1. PaMth1 decreases protein carbonylation in P. anserina cells.

    “Constitutive over-expression of PaMth1 in P. anserina results in a reduced carbonylation of proteins”

    Cellsconstitutive over-expression

    Over-expression of an S-adenosylmethionine-dependent methyltransferase leads to an extended lifespan of Podospora anserina without impairments in vital functions

    Aging cellJul 24, 2008

More on Protein carbonylation

Lifespan

upin P. anserina cells1

1 study

  1. PaMth1 extends lifespan in P. anserina cells.

    “Constitutive over-expression of PaMth1 in P. anserina results in a reduced carbonylation of proteins and an extended lifespan without impairing vital functions”

    Cellsconstitutive over-expression

    Over-expression of an S-adenosylmethionine-dependent methyltransferase leads to an extended lifespan of Podospora anserina without impairments in vital functions

    Aging cellJul 24, 2008

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