pal-1

Gene

2 papers study it4 findings

Taxon

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 4 more
  • Model organisms2

Effects

4

Body length

no changein worms1

1 study
  1. pal-1 has no effect on body length in worms.

    “auxin-induced degradation of PAL-1 starting from the L1 larval stage does not affect body length development”

    Model organismsauxin-induced degradation starting from L1 larval stage

    Investigation of PAL-1 requirement in C. elegans physiology using the auxin-inducible degradation system

    microPublication biology

Fertility

downin worms1

1 study
  1. pal-1 impairs fertility in worms.

    “auxin-induced degradation of PAL-1 starting from the L1 larval stage does not affect body length development but renders the animal sterile”

    Model organismsauxin-induced degradation starting from L1 larval stage

    Investigation of PAL-1 requirement in C. elegans physiology using the auxin-inducible degradation system

    microPublication biology

Lifespan

downin worms1

1 study
  1. pal-1 shortens lifespan in worms.

    “auxin-induced degradation of PAL-1 starting from the L1 larval stage does not affect body length development but renders the animal sterile and shortens lifespan.”

    Model organismsauxin-induced degradation starting from L1 larval stage

    Investigation of PAL-1 requirement in C. elegans physiology using the auxin-inducible degradation system

    microPublication biology

Stress resistance

upin worms1

1 study
  1. pal-1 increases stress resistance in worms.

    “Knockdown of pal-1 inhibits the activation of ccf-1 dependent stress genes and reduces C. elegans stress resistance.”

    Model organismspal-1 knockdown

    CCR4-NOT subunit CCF-1/CNOT7 promotes transcriptional activation to multiple stress responses in Caenorhabditis elegans

    Aging cell

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