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Mnm

Gene

1 paper2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Hunan Normal University and 1 more
  • Model organisms1

Effects

2

Lifespan

downin flies1

1 study

  1. Mnm shortens lifespan in flies.

    “Furthermore, the knockdown of dMnM in indirect flight muscle (IFM) reduced climbing ability and shortened lifespan.”

    Model organismsin indirect flight muscle

    Regular Exercise Rescues Heart Function Defects and Shortens the Lifespan of Drosophila Caused by dMnM Downregulation

    International journal of environmental research and public healthDec 9, 2022

Cardiac function

downin flies1

1 study

  1. Mnm impairs cardiac function in flies.

    “dMnM (MYOM2 homologs) knockdown in cardiomyocytes resulted in diastolic cardiac defects (diastolic dysfunction and arrhythmias)”

    Model organismsin cardiomyocytes

    Regular Exercise Rescues Heart Function Defects and Shortens the Lifespan of Drosophila Caused by dMnM Downregulation

    International journal of environmental research and public healthDec 9, 2022

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