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MIR1292

Gene

1 paper studies it3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Effects

3

Ectopic bone formation

downin animals1

1 study

  1. MIR1292 inhibits ectopic bone formation.

    “Furthermore, miR-1292 upregulation inhibited ectopic bone formation in vivo.”

    AnimalsmiR-1292 upregulation; in vivo

    MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway

    Aging and diseaseDec 4, 2018

osteogenic differentiation

downin human cells1

1 study

  1. MIR1292 inhibits osteogenic differentiation in human cells.

    “Overexpression of miR-1292 notably accelerated hADSC senescence and restrained osteogenesis, whereas its knockdown decreased senescence and enhanced osteogenic differentiation.”

    Cellsshown by overexpression and knockdownhuman adipose-derived mesenchymal stem cell

    MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway

    Aging and diseaseDec 4, 2018

Cellular senescence

upin human cells1

1 study

  1. MIR1292 increases cellular senescence in human cells.

    “Overexpression of miR-1292 notably accelerated hADSC senescence and restrained osteogenesis, whereas its knockdown decreased senescence and enhanced osteogenic differentiation.”

    Cellsshown by overexpression and knockdownhuman adipose-derived mesenchymal stem cell

    MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway

    Aging and diseaseDec 4, 2018

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