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MIR-27B

There is 1 paper on MIR-27B in aging research: none in people yet, 1 in cells.

Gene

1 paper studies it2 findings

HGNCNCBI GeneTaxon

See all 1 papers on MIR-27B

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Cells: a single group. Worms or flies, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 2 more
  • Cells1

Effects

2

Mesenchymal stem cell migration

downin pig cells1

1 study

  1. MIR-27B decreases mesenchymal stem cell migration in pig cells (shown by inhibition of miR-27b in cultured MSCs).

    “Inhibition of miR-27b in cultured MSCs downregulated p16 and MARP3 genes, and increased MSC migration.”

    Cellsshown by inhibition of miR-27b in cultured MSCsadipose tissuen = 6

    Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway

    Cell transplantation

P16 expression

upin pig cells1

1 study

  1. MIR-27B increases P16 expression in pig cells (shown by inhibition of miR-27b in cultured MSCs).

    “Inhibition of miR-27b in cultured MSCs downregulated p16 and MARP3 genes, and increased MSC migration.”

    Cellsshown by inhibition of miR-27b in cultured MSCsadipose tissuen = 6

    Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway

    Cell transplantation

More on P16 expression

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