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mig-22

Gene

1 paper2 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Japan Society for the Promotion of Science and 3 more
  • Model organisms1

Effects

2

Healthspan

upin worms1

1 study

  1. mig-22 improves healthspan in worms.

    “a gain-of-function mutation in MIG-22, the chondroitin polymerizing factor (ChPF), results in elevated chondroitin levels and a significant extension of both the lifespan and healthspan in C. elegans”

    Model organismsmig-22(gf) gain-of-function mutation

    Endogenous chondroitin extends the lifespan and healthspan in C. elegans

    Scientific reportsFeb 27, 2024

Lifespan

upin worms1

1 study

  1. mig-22 extends lifespan in worms.

    “a gain-of-function mutation in MIG-22, the chondroitin polymerizing factor (ChPF), results in elevated chondroitin levels and a significant extension of both the lifespan and healthspan in C. elegans”

    Model organismsmig-22(gf) gain-of-function mutation

    Endogenous chondroitin extends the lifespan and healthspan in C. elegans

    Scientific reportsFeb 27, 2024

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