math-33

math-33 increases DAF-16 protein stability in worms.

“We found that MATH-33 actively stabilizes DAF-16 protein levels when IIS is downregulated.”

Reviewwhen insulin/IGF-1-like signaling is downregulated

The C. elegans Ortholog of USP7 controls DAF-16 stability in Insulin/IGF-1-like signaling

Worm·Nov 17, 2015