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LTB4R

Gene

2 papers study it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Royal Adelaide Hospital
  • Humans2

Interventions

1

Prednisolone

upin human cells2

2 studies

  1. Prednisolone increases LTB4R in human cells.

    “Treatment with 1 μM prednisolone in vitro resulted in upregulation of BLTR1 expression in pro-inflammatory CD28nullCD8+ cells”

    CellsCD28nullCD8+ cells1 μM

    BLTR1 Is Decreased in Steroid Resistant Pro-Inflammatory CD28nullCD8+ T Lymphocytes in Patients with COPD-The Spillover Hypothesis Explained?

    Biology

  2. Prednisolone increases LTB4R in human cells.

    “Treatment with 1μM prednisolone in vitro resulted in upregulation of BLTR1 expression in pro-inflammatory CD28nullCD8+ cells”

    Cellsin vitro1 μM

    BLTR1 is decreased in steroid resistant pro-inflammatory CD28nullCD8+ T lymphocytes in patients with COPD - the spillover hypothesis explained?

    Research SquarePreprint

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