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knownaging-relatedgenes

Gene

2 papers2 findings

Taxon

  • In silico2

Associations

2

Supervised machine learning pipeline

upin silico1

1 study

  1. supervised machine learning pipeline predicts knownaging-relatedgenes in silico (91% of the top 438 ranked genes were known genes on GenAge).

    “our ranked output showed that 91% of the top 438 ranked genes consisted of known genes on GenAge”

    In silicoTop 438 ranked genes; comparison with GenAge

    Supervised machine learning with feature selection for prioritization of targets related to time-based cellular dysfunction in aging

    bioRxiv (Cold Spring Harbor Laboratory)Jun 28, 2022Preprint

Targets of lifespan-extending drugs

upin silico1

1 study

  1. targets of lifespan-extending drugs are associated with knownaging-relatedgenes in silico.

    “we found a modest but significant overlap between targets of lifespan-extending drugs and known aging-related genes”

    In silico

    The DrugAge database of aging-related drugs

    Aging cellMar 16, 2017

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