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IMPDH2

Gene

2 papers2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans1
  • Cells1

Effects

2

Cellular senescence

upin human cells1

1 study

  1. IMPDH2 increases cellular senescence in human cells.

    “They promote human decidualization and naturally enhance cellular senescence.”

    Cellsendometrium

    Regulation and function of inosine monophosphate dehydrogenase 2 cytoophidia during mouse and human decidualization

    Cellular signallingApr 8, 2025

More on Cellular senescence

DNA damage response

upin mice1

1 study

  1. IMPDH2 induces DNA damage response in mice.

    “IMPDH2 cytoophidia can induce nucleolar stress and DNA damage in mice.”

    Animalsin mouse decidual cells

    Regulation and function of inosine monophosphate dehydrogenase 2 cytoophidia during mouse and human decidualization

    Cellular signallingApr 8, 2025

More on DNA damage response

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