HSF2

1. HSF2 extends lifespan in flies.

   “ectopic expression in D. melanogaster of hsal HSF2 leads to enhanced survival compared to hsal HSF1 following heat stress, as well as extended lifespan.”

   Model organismsectopic expression of ant HSF2

   Long lifespan is maintained by a unique Heat Shock Factor in reproductive ants

   bioRxiv (Cold Spring Harbor Laboratory)·8 Apr 2022Preprint

1. HSF2 increases survival following heat stress in flies.

   “ectopic expression in D. melanogaster of hsal HSF2 leads to enhanced survival compared to hsal HSF1 following heat stress, as well as extended lifespan.”

   Model organismsectopic expression of ant HSF2 compared with ant HSF1

   Long lifespan is maintained by a unique Heat Shock Factor in reproductive ants

   bioRxiv (Cold Spring Harbor Laboratory)·8 Apr 2022Preprint

1. HSF2 increases heat shock response gene expression in H. saltator.

   “This HSR gene elevation is driven in part by gamergate-specific constitutive upregulation of a heat shock transcription factor gene most similar to mammalian HSF2”

   Model organismsgamergates in the absence of heat stressfemales

   Long lifespan is maintained by a unique Heat Shock Factor in reproductive ants

   bioRxiv (Cold Spring Harbor Laboratory)·8 Apr 2022Preprint

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