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HIV-1TRANSGENE

Gene

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of Mental Health and 4 more
  • Humans1

Effects

2

Temporal processing

downin rats1

1 study

  1. HIV-1TRANSGENE impairs temporal processing in rats.

    “HIV-1 Tg rats exhibited prominent alterations in the progression of temporal processing relative to control animals”

    Animalsaging HIV-1 transgenic model

    Intraneuronal β-Amyloid Accumulation: Aging HIV-1 Human and HIV-1 Transgenic Rat Brain

    Viruses

Intraneuronal β-amyloid accumulation

upin rats1

1 study

  1. HIV-1TRANSGENE increases intraneuronal β-amyloid accumulation in rats.

    “In aging HIV-1 Tg rats, double immunohistochemistry staining revealed abnormal intraneuronal β-amyloid accumulation in the prefrontal cortex (PFC) and hippocampus, relative to F344/N control rats.”

    Animalsaging HIV-1 transgenic modelprefrontal cortex and hippocampus

    Intraneuronal β-Amyloid Accumulation: Aging HIV-1 Human and HIV-1 Transgenic Rat Brain

    Viruses

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