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Intraneuronal β-amyloid accumulation

Biomarker

1 paper studies it2 findings

  • Humans1

Upstream

1

HIV-1TRANSGENE

upin rats1

1 study

  1. HIV-1TRANSGENE increases intraneuronal β-amyloid accumulation in rats.

    “In aging HIV-1 Tg rats, double immunohistochemistry staining revealed abnormal intraneuronal β-amyloid accumulation in the prefrontal cortex (PFC) and hippocampus, relative to F344/N control rats.”

    Animalsaging HIV-1 transgenic modelprefrontal cortex and hippocampus

    Intraneuronal β-Amyloid Accumulation: Aging HIV-1 Human and HIV-1 Transgenic Rat Brain

    VirusesJun 10, 2022

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Associations

1

HIV-1-associated neurocognitive disorders

upin humans1

1 study

  1. HIV-1-associated neurocognitive disorders are associated with intraneuronal β-amyloid accumulation in humans.

    “in post-mortem HIV-1 seropositive individuals with HAND, intraneuronal β-amyloid accumulation was observed in the dorsolateral PFC and hippocampal dentate gyrus.”

    Humansolder HIV-1 seropositive individuals with HANDdorsolateral PFC and hippocampal dentate gyrus

    Intraneuronal β-Amyloid Accumulation: Aging HIV-1 Human and HIV-1 Transgenic Rat Brain

    VirusesJun 10, 2022

More on HIV-1-associated neurocognitive disorders

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